Overview of Chosen Chemical Compounds and Intermediates

one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity connected with bortezomib, a proteasome inhibitor Utilized in the treatment of various myeloma. Its synthesis or examine is important for making certain the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug Utilized in the treatment method of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-ten-one): A crucial compound within the synthesis of imatinib, a drug that targets precise different types of cancer, which include Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats different cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They're intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their analyze is important for optimizing the output method and making CAS NO. 134790-39-9 sure significant purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is utilised to deal with breast most cancers, and these intermediates are involved in its manufacturing.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the therapy of breast cancer. Numerous intermediates help in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug helpful in managing cancers for instance ovarian, breast, and lung most cancers.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal cancer and small mobile lung cancer.
three-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is involved in the synthesis of adamantane derivatives, which have different programs, such as antiviral Qualities.
Vildagliptin Intermediates: Utilized in the production of vildagliptin, an oral drug for sort two diabetic issues that inhibits the enzyme DPP-four to control blood sugar ranges.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone 5(10)-triene-3 (CAS NO. 61259-48-one): This compound is involved in the synthesis of varied gluconic acid derivatives, that happen to be Utilized in meals, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication utilised to manage style two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).

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